a 30 mg/kg loading dose of acetaminophen was more effective than a 15 mg/kg maintenance dose in febrile children.
نویسنده
چکیده
منابع مشابه
Antipyretic efficacy of an initial 30-mg/kg loading dose of acetaminophen versus a 15-mg/kg maintenance dose.
OBJECTIVE To compare the antipyretic efficacy of an initial 30-mg/kg acetaminophen loading dose versus a 15-mg/kg maintenance dose. METHODS A double-blind, parallel-group, randomized clinical trial was conducted. A total of 121 febrile (rectal temperature between 39 degrees C and 40 degrees C) but otherwise healthy outpatients who were 4 months to 9 years of age and weighed 4 to 26 kg were as...
متن کاملA Comparison of the Antipyretic Effect of Acetaminophen and Ibuprofen in Febrile Children Hospitalized At Amir-Al-Momenin Hospital in Semnan, Iran
Prolonged and high fever may cause various disturbances in children, and prompt lowering of fever is essential. Therefore, an appropriate treatment aimed at rapid lowering of fever and keeping the child afebrile is mandated. There have been various studies on the different types of anti-pyretic treatment in children. The aim of our study is to compare the antipyretic effect of Acetaminophen a...
متن کاملEfficacy and safety of acetaminophen vs ibuprofen for treating children's pain or fever: a meta-analysis.
OBJECTIVE To summarize studies testing the efficacy and safety of single-dose acetaminophen and ibuprofen for treating children's pain or fever. DATA SOURCES Reports were gathered by searching computerized databases (from their inception through May 2002) and registries, relevant journals, and bibliographies of key articles. STUDY SELECTION Seventeen blinded, randomized controlled trials wi...
متن کاملAntipyretic treatment in young children with fever: acetaminophen, ibuprofen, or both alternating in a randomized, double-blind study.
OBJECTIVE To compare the antipyretic benefit of acetaminophen or ibuprofen monotherapy with an alternating regimen of both drugs in young children aged 6 to 36 months. DESIGN Randomized, double-blind, parallel-group trial. SETTING Three primary pediatric community ambulatory centers in central Israel. PARTICIPANTS A total of 464 children aged 6 to 36 months with fever. INTERVENTION Infa...
متن کاملEqual antipyretic effectiveness of oral and rectal acetaminophen: a randomized controlled trial [ISRCTN11886401]
BACKGROUND The antipyretic effectiveness of rectal versus oral acetaminophen is not well established. This study is designed to compare the antipyretic effectiveness of two rectal acetaminophen doses (15 mg/kg) and (35 mg/kg), to the standard oral dose of 15 mg/kg. METHODS This is a randomized, double-dummy, double-blind study of 51 febrile children, receiving one of three regimens of a singl...
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ورودعنوان ژورنال:
- Evidence-based nursing
دوره 5 2 شماره
صفحات -
تاریخ انتشار 2002